$VRTX

Vertex Pharmaceuticals Incorporated · NasdaqGS · Healthcare

523.93-11.24 (-2.10%)
Market cap
132.80B
Volume
832.5K
P/E
29.90
Day range
522.92 – 532.99
52w range
403.16 – 560.25
Analyst target
571.46

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$VRTX -2.10% at 523.93
David Tepper and 2 other tracked billionaires hold it.
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Company summary

Vertex Pharmaceuticals Incorporated operates as a biotechnology company in the United States, Europe, and internationally. The company offers transformative medicines for people with serious diseases with a focus on specialty markets, such as cystic fibrosis (CF), sickle cell disease (SCD), transfusion dependent beta thalassemia (TDT), and acute pain. It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor. The company also develops CASGEVY for the treatment of SCD and TDT; JOURNAVX for the treatment of acute pain in adults; VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1/2 clinical trial; inaxaplin for the treatment of APOL1-mediated kidney disease, which is in single Phase 2 trial; VX-264 for treating Type 1 Diabetes; VX-670 for the treatment of myotonic dystrophy type 1; and VX-407, a small molecule corrector for the treatment of autosomal dominant polycystic kidney disease. In addition, the company also operates as a clinical-stage pharmaceutical company, that focuses on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. The company sells its products primarily to specialty pharmacy and distributors, wholesalers, retail pharmacies, hospitals, and clinics. Vertex Pharmaceuticals Incorporated has a strategic collaboration with AbCellera Biologics Inc. to research, develop, manufacture, and commercialize multispecific T-cell engagers (TCEs) for autoimmune diseases and other conditions. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

Industry: BiotechnologyEmployees: 6,400HQ: United StatesWebsite

Institutional ownership

Institutions hold 98.31% · insiders 0.21% · 2,454 institutions

HolderSharesValue% heldReported
Capital World Investors26.12M$13.68B10.29%2026-06-30
Blackrock Inc.24.11M$12.63B9.50%2026-06-30
Capital Research Global Investors19.49M$10.21B7.68%2026-06-30
Vanguard Capital Management LLC16.58M$8.69B6.53%2026-06-30
State Street Corporation11.87M$6.22B4.68%2026-06-30
Invesco Ltd.8.04M$4.21B3.17%2026-06-30
JPMORGAN CHASE & CO6.52M$3.41B2.57%2026-06-30
Geode Capital Management, LLC6.02M$3.15B2.37%2026-06-30
Vanguard Portfolio Management LLC4.88M$2.56B1.92%2026-06-30
Capital International Investors4.70M$2.46B1.85%2026-06-30

Hedge fund & billionaire activity

Insider transactions

InsiderRoleTransactionSharesDate
BRENNAN DANIEL JDirectorStock Award(Grant) at price 503.47 per share.795.002026-10-20
AMBROSE KRISTENOfficerStock Award(Grant) at price 0.00 per share.5.0K2026-08-28
SACHS BRUCE IDirectorStock Gift at price 0.00 per share.6.0K2026-08-27
TATSIS OURANIAOfficerStock Award(Grant) at price 0.00 per share.8.3K2026-07-21
SACHDEV AMITOfficerStock Award(Grant) at price 0.00 per share.8.3K2026-07-21
MCKECHNIE DUNCAN J.OfficerSale at price 519.00 per share.1.5K2026-07-02
TATSIS OURANIAOfficerSale at price 524.99 per share.1.5K2026-07-02
LIU JOYOfficerSale at price 502.71 per share.828.002026-07-01
BOZIC CARMENOfficerSale at price 482.50 per share.596.002026-06-26
BOZIC CARMENOfficerSale at price 462.17 per share.1.0K2026-06-18
BOZIC CARMENOfficerSale at price 450.00 per share.4.1K2026-06-15
BOZIC CARMENOfficerSale at price 450.00 per share.1.7K2026-06-05

Analyst ratings

Consensus score 1.66 (1 = strong buy, 5 = sell) · mean target 571.46

  • RBC CapitalOutperformmain2026-10-08
  • UBSBuymain2026-09-28
  • Truist SecuritiesBuymain2026-08-05
  • BarclaysOverweightmain2026-08-05
  • TD CowenBuymain2026-08-04
  • Cantor FitzgeraldOverweightmain2026-08-04
  • Canaccord GenuityHoldmain2026-08-04
  • UBSBuymain2026-07-13
  • Truist SecuritiesBuymain2026-07-13
  • RBC CapitalOutperformmain2026-07-07

Earnings

Next report: 2026-11-02

QuarterEPS actualEPS estimateSurprise
3Q20254.804.580.22
4Q20255.035.15-0.12
1Q20264.474.310.16
2Q20264.734.75-0.02

SEC filings

  • 8-KCorporate Changes & Voting Matters2026-10-20Open
  • 8-KCorporate Changes & Voting Matters2026-09-01Open
  • 10-QPeriodic Financial Reports2026-08-04Open
  • 8-KCorporate Changes & Voting Matters2026-08-03Open
  • 8-KCorporate Changes & Voting Matters2026-07-07Open
  • S-8 POSOffering Registrations2026-05-13Open
  • 10-QPeriodic Financial Reports2026-05-05Open
  • 8-KCorporate Changes & Voting Matters2026-05-04Open
  • DEFA14AProxy Statements2026-04-29Open
  • DEF 14AProxy Statements2026-04-02Open

Latest VRTX news

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